CORDIS Project
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The project aims to characterize the immune responses related to inflammatory bowel disease by studying microbiota-specific T cells. It seeks to identify mechanisms that influence disease severity and potential new therapeutic targets for treatment.
Dysregulation in the balance of CD4+ T helper cell populations can severely alter susceptibility to a number of chronic inflammatory diseases, including inflammatory bowel disease (IBD).
The incidence of IBD is dramatically increasing in Europe and worldwide and its therapy represents an important unmet medical need, since a significant proportion of patients fail to respond to currently available immunotherapies.
Therefore, a better characterization of the immunological events underlying each f…
KAROLINSKA INSTITUTET
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