CORDIS Project
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HBOX Therapies GmbH is developing MiRA, a miniaturized respiratory assist device aimed at treating acute lung failure patients. This innovative therapy offers a non-invasive alternative to mechanical ventilation, enhancing oxygenation and carbon dioxide removal while patients remain awake, thus improving outcomes and r…
Acute lung failure (ALF) is the third leading cause of death globally and is characterised by severe respiratory impairment.
When non-invasive ventilation (NIV) fails, the treatment escalates to invasive mechanical ventilation (IMV) - the current standard of care for ALF. IMV is highly invasive, with a high risk of complications and an avg. in-hospital mortality rate of 35%, costing thousands of euros per patient.
Hospitals have signalled an unmet need for safe and adequate alternatives to IMV i…
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