CORDIS Project
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This project utilizes three-dimensional organoid cultures derived from human stem cells to study brain development and neurological disorders. It aims to identify human-specific brain patterning and the genetic factors involved in diseases like microcephaly and schizophrenia.
Most of our knowledge on human development and physiology is derived from experiments done in animal models.
While these experiments have led to a comprehensive understanding of the principles of neurogenesis, animal models often fall short of modelling many of the most common neurological disorders.
Recent experiments have revealed characteristic striking differences in brain development between rodents and primates and may provide an explanation for this problem.The goal of this proposal is to…
INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
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