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The MiMING project investigates the role of microtubules and motor proteins in the cell division process of zebrafish and Drosophila embryos. It aims to understand how these components contribute to meroblastic furrow ingression, which is crucial for embryonic development.
Cell division is the fundamental process for cell differentiation and tissue formation in early embryogenesis.
Mainly depending on the distribution and amount of yolk, fertilized embryos undergo holoblastic and meroblastic divisions.
Holoblastic division can be found in most mammalian embryos including mouse embryo, in which actomyosin forms contractile cytoskeletal ring and divides the zygote into two daughter cells.
In contrast, cell division in fish and insect embryos, such as zebrafish and D…
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