CORDIS Project
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The MIMIC project aims to uncover the signaling mechanisms of integrins, which are vital for cellular communication and implicated in various diseases. By combining computational modeling with experimental techniques, it seeks to identify new integrin ligands and develop innovative therapeutic agents.
Multicellular life depends on the effective communication between cells and their surroundings.
One of the primary conduits for cellular interactions is the membrane-embedded receptor family of integrins.
Integrins are crucial for several key biological processes, from blood clotting, to proper immune response.
Integrin misregulation is at the heart of several diseases, such as Crohn’s disease, MS, or cancer, and integrins are targeted by several viruses as entry points.
Yet, our current drugs a…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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