CORDIS Project
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The MiMi-AD project investigates the role of gut microbiota in Alzheimer's disease progression, focusing on how exercise-induced changes in gut bacteria may influence microglial activity. Using a mouse model, the project aims to identify microbial metabolites that could help clear amyloid-beta and reduce neuroinflammat…
Alzheimer’s disease (AD) affects over 55 million people worldwide, with no effective treatments currently available.
Understanding early-stage mechanisms of the disease is critical to developing new therapeutic approaches.
Microglial cells, key regulators of amyloid-beta (Aβ) clearance and neuroinflammation, are implicated in the progression of AD.
Emerging evidence suggests that the gut microbiota, through its influence on microglial function, may play a pivotal role in AD pathogenesis.
However…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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