CORDIS Project
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This research investigates the role of centrosomes in microtubule organization and their implications in cancer and genetic diseases. It focuses on characterizing proteins involved in centrosome function and their effects on cellular processes.
Centrosomes are multifunctional organelles crucial for a large number of cellular functions including the organization of microtubules.
In mitosis centrosomes contribute to assembly, orientation and function of the mitotic spindle, which is important for proper segregation of the chromosomes.
Defects in centrosome number and function are strongly associated with the cancer phenotype and centrosomes offer potential new targets for anti-mitotic cancer drugs.
Recent data suggests that microtubule o…
FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)
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