CORDIS Project
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This project investigates the role of microglia, the immune cells of the central nervous system, in temporal lobe epilepsy. By isolating and analyzing these cells, the research aims to clarify their functions during brain repair processes and differentiate them from infiltrating macrophages, potentially revealing new t…
Microglia are the primary immune cells of the central nervous system (CNS) and are considered potential key players in the pathophysiology of temporal lobe epilepsy (TLE).
Indeed, microglia activation is observed directly after status epilepticus and during epileptogenesis, both in TLE animal models as well as in human patients.
Since microglia activation is correlated with the presence of pro-inflammatory factors, they are considered to be harmful.
Recent findings, however, suggest that inflamm…
UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA
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