CORDIS Project
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This project investigates the different states of microglia, the brain's immune cells, to understand their roles in neuroinflammation and brain repair. By mapping gene expression changes over time and space, it aims to uncover how these states function and develop, potentially leading to new therapeutic strategies for…
Microglia, the macrophages of the brain, are critical regulators of many neurobiological functions and implicated by human genetics in several central nervous system diseases.
Recent studies have revealed that microglia can adopt distinct co-existing subtypes, termed 'states'.
Microglial states appear especially in the context of damage, disease or repair and understanding these states may lead to the ability to precisely modulate neuroinflammation.
However, due to a lack of datasets and tools,…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
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