CORDIS Project
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This project focuses on understanding ischemia-reperfusion injury in heart disease, aiming to identify microRNAs that influence cardiomyocyte resistance to this damage. The research seeks to uncover new therapeutic targets for myocardial infarction treatment.
Ischemia-reperfusion injury is a major cause of morbidity and mortality transversal to different clinical settings and pathologies, including myocardial infarction.
Ischemia is characterised by insufficient supply of blood to tissues causing tissue oxygen deprivation.
Importantly, damage by prolonged ischemia is further aggravated by reperfusion, leading to irreversible tissue damage.
Identifying and understanding the factors contributing to ischemia-reperfusion injury is essential to counteract…
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