CORDIS Project
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This project investigates how the blood-brain barrier develops during early brain formation, focusing on interactions between microglia and vascular cells. It aims to understand the influence of maternal microbiota on this process, which is crucial for brain health and disease.
Brain functioning can be influenced by body ecosystem signals conveyed through the vasculature and regulated by the blood-brain barrier (BBB), a selective and modulable barrier that controls which substances and cells enter the brain.
Structural or functional BBB deficits are found in many brain diseases, from neurodevelopment to neurodegeneration, thus understanding how the BBB develops holds critical significance for both biologists and clinicians.
Yet, we still lack fundamental knowledge on h…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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