CORDIS Project
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The MIAMI project investigates chronic joint diseases, particularly seronegative arthritis, focusing on innate immune mechanisms. It aims to develop personalized treatment strategies by identifying specific inflammatory pathways and translating these findings into novel biomarkers for better disease management.
In chronic joint disease, only a subgroup of patients has classical autoantibodies, while the other variants are seronegative arthritis syndromes with a predominance of innate immune disturbances.
These forms of joint diseases frequently show extra-articular manifestations of epithelial tissues like skin and gut.
On the molecular level, innate immune activation and the release of damage associated molecular pattern proteins (DAMPs) of the S100 family are important mechanisms of initiation and pe…
Westfälische Wilhelms-Universität Münster
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STICHTING RADBOUD UNIVERSITEIT
Netherlands, Nijmegen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Belgium, Gent
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Netherlands, Utrecht
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Ireland, Dublin
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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