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METMAP investigates the role of extracellular vesicles in melanoma metastasis. By examining how different melanoma cell states contribute to the formation of pre-metastatic niches, the project aims to identify new therapeutic targets to disrupt cancer spread.
Every 2 minutes someone in the world is diagnosed with melanoma, so by the time you read this application dozens of new melanoma cases will be detected.
Beyond its growing incidence, cutaneous melanoma is the most aggressive type of skin cancer and notorious for its high metastatic propensity, which constitutes the primary cause of death for these patients.
Cellular heterogeneity and plasticity are key features of melanoma, supporting disease progression.
The host laboratory has recently charted…
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