CORDIS Project
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This project investigates the role of adenosine methylation in regulating microRNAs involved in epilepsy. By profiling these modifications in brain tissue and evaluating their effects on neuronal function, the research aims to uncover new therapeutic strategies for epilepsy treatment.
Evidence is emerging that persistent changes in gene expression regulation and post-transcriptional regulation underlies the epileptogenic process.
The current proposal builds on preliminary data which suggests that microRNAs (miRNA), which have recently emerged as critical regulators of epileptogenesis, may be subjected to adenosine methylation (m6A), and that this process may also be disrupted in epilepsy, representing an unexplored layer of gene expression regulation likely to influence neuro…
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
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ROYAL COLLEGE OF SURGEONS IN IRELAND
Ireland, Dublin
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Denmark, Aarhus N
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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