CORDIS Project
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This project investigates how macrophages, key immune cells, respond to environmental changes by examining the interplay between their metabolic and transcriptional activities. By utilizing genomic and metabolomic techniques, the research aims to uncover mechanisms that control macrophage activation and gene expression…
Organismal responses to environmental threats involve the activation of both resident and monocyte-derived macrophages, key components of the innate immune system.
Macrophages are capable of rapidly sensing micro-environmental changes and of reacting with distinct activities ranging from specialised homeostatic functions, to the activation of effector functions in tissue immune surveillance.
These diverse biological outcomes are brought about by the coordinated rewiring of both metabolic and tra…
HUMANITAS UNIVERSITY
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