CORDIS Project
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This project investigates the role of cancer stem cells in metastasis, focusing on their ability to promote tumor growth and recruit supportive cells from the bone marrow. By studying lung and liver metastasis models, the project aims to uncover mechanisms driving these processes and develop new treatment strategies.
Metastasis disease is the leading cause of cancer-related mortality with very few effective treatment options available for patients.
Metastases are characterized by the presence of vascular proliferation, a subpopulation of stem-like cells and infiltration by various bone marrow derive cells (BMDCs). BMDCs have been shown to provide the premetastatic niches that promote the angiogenic process and create an environment permissive for tumor cell homing and colonization.
The cancer stem cell (C…
FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA
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