CORDIS Project
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The METASPINE project aims to develop a quantitative computational model to predict fracture risk in cancer patients with lytic spinal metastases. By reproducing bone lesions and conducting mechanical tests, the project seeks to enhance understanding of how these lesions affect vertebrae stability.
Lytic spinal metastases are frequent in cancer patients and can weaken vertebrae, increasing the risk of fracture and leading to spine instability.
Qualitative scoring systems are used by oncologists and orthopaedic surgeons to decide if the metastatic vertebrae need to be surgically treated.
However these guidelines are not accurate for all those patients with middle-size lesions.
An accurate, quantitative and mechanistic computational model would improve the prediction of the risk of fractur…
THE UNIVERSITY OF SHEFFIELD
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