CORDIS Project
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This research explores the connection between metabolic stress and immune responses, particularly in the context of obesity-related diseases. It focuses on understanding how endoplasmic reticulum stress influences inflammation and could lead to targeted therapies for cardiometabolic syndrome.
A close functional and molecular integration between metabolic and immune systems is crucial for systemic homeostasis and its’ deregulation is causally linked to obesity and associated diseases including insulin resistance, diabetes and atherosclerosis and known as cardiometabolic syndrome (CMS).
Metabolic overload initiates a chronic inflammatory and stress response known as metaflammation and promotes the complications of CMS.
The precise molecular mechanisms linking metabolic stress to immune…
BILKENT UNIVERSITESI VAKIF
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