CORDIS Project
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This project investigates the mechanisms of synaptic plasticity in neurons affected by Fragile X syndrome, a leading cause of inherited intellectual disability and autism. By studying neuronal activity and synaptic structures in a mouse model, the research aims to uncover how these processes are altered and identify po…
Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability (ID), and the leading known genetic cause of autism.
This dominant phenotype represents a huge hindrance for clinicians in the treatment of FXS because the underlying neuronal deficits remain unknown.
Individual neurons store information as we learn and acquire new information by modifying their connections with nearby neurons, a process called synaptic plasticity.
This refers to activity-dependent long-term c…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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