CORDIS Project
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This project investigates the role of interorganelle communication in metabolic dysfunction-associated fatty liver disease. By developing imaging probes, it aims to understand the interactions between mitochondria and peroxisomes and their impact on lipid metabolism.
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the liver manifestation of metabolic syndrome, consisting in a hepatic accumulation of lipids.
While MAFLD is predicted to concern near 50% of the global adult population in 2040, no medication has been developed to counter its progression.
Recent studies have identified a novel interorganelle communication in the liver, that consists in the endoplasmic reticulum engaging contact sites with both mitochondria and peroxisome, hence te…
UNIVERSITA DEGLI STUDI DI PADOVA
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