CORDIS Project
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This project investigates how specific metabolic states may increase the risk of liver cancer, particularly in individuals with diabetes and obesity. By analyzing metabolic changes in liver cells, the research aims to establish a causal link between altered metabolism and cancer development, ultimately informing new pr…
Continuous research on cancer has unraveled genetic alterations and subsequently signal transduction pathways changed in a cancer cell, thereby it emerged that many of the genetic factors commonly altered in cancer cells often target metabolic genes.
An altered metabolism allows cancer cells to sustain their proliferative needs.
Yet, whether altered metabolic fluxes and metabolite concentrations, which define the metabolic state of a cell, are only a consequence or can be a cause of cancer is a…
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