CORDIS Project
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This research aims to understand the regulation of metabolic networks using yeast as a model organism. By integrating genetics with metabolomics and proteomics, the project seeks to elucidate how metabolic pathways influence aging and identify new interactions that could inform therapeutic strategies for age-related di…
The metabolic network has a modular architecture, is robust to perturbations, andresponds to biological stimuli.
The balance of the network, and the passageway ofnetwork substructures to operate at different activity, requires intensive interactionsbetween the metabolic network, the transcriptome and the proteome.
However, thebiochemical mechanisms monitoring the metabolic network are only barely understood.Changes in network activity are often mediated through so called reporter metabolites:gen…
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