CORDIS Project
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This project focuses on understanding how breast cancer cells survive in the bloodstream, which is crucial for developing better treatments. By creating animal models, researchers aim to explore the role of specific signaling mechanisms in cancer cell dissemination and metastasis.
Breast cancer is the most common cancer in women and, after lung cancer, the second leading cause of cancer-related deaths.
The most important factor influencing the outcome of patients with an invasive cancer is whether the tumour has spread regionally or systemically.
Breast cancer dissemination is a multi-step process, affected by intrinsic, as well as by microenvironmental factors.
Metastases start out as single cells that detach from the primary tumour and travel to distal locations.
The nu…
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
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