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The MESOTAS-SIEVE project focuses on developing a 3D brain-on-chip bioreactor that mimics human neuronal networks for drug testing. This innovative system aims to improve the understanding of brain function and enhance drug efficacy and toxicity assessments.
This project will demonstrate the technical and commercial viability of the MESOTAS-SIEVE bioreactor, a novel 3D brain-on-chip microculture system.
This allows the culturing and in vitro functional analysis of neuronal networks that mimic the human brain in a physiologically much more relevant way than conventional cell culture systems or animal models.
Therefore, the MESOTAS-SIEVE system has great potential towards the realisation of tissue models of the brain for drug efficacy and toxicity as…
TECHNISCHE UNIVERSITEIT EINDHOVEN
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