CORDIS Project
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This project explores the role of specialized niche cells in maintaining skeletal stem cells and their function. By using zebrafish models, it aims to understand the metabolic processes that support skeletal health and inform future therapies for metabolic diseases.
The continued health of many of our organs, including the skeleton, relies on the function of specialized stem cells.
These stem cells reside in niches that support their long-term maintenance.
Disruption of the niche due to aging, injury, or genetic mutations, can lead to declines in stem cells and a failure to maintain and repair tissues.
Compared to our understanding of the stem cells that maintain and repair our skeleton, we know much less about the cell types that constitute their niche.
My…
Masarykova univerzita
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