CORDIS Project
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This project examines the molecular mechanisms that enable the formation of lasting memories in adults, focusing on the role of specific receptors and genes. It aims to uncover how these processes can be influenced to improve memory function in various conditions.
When an adult mammal acquires new skills and new knowledge, the degree to which transition will occur from temporary to permanent memories of such events is governed by factors such as emotional weight and importance of the experiences for survival.
To execute the necessary structural synaptic reorganisations needed to permanently embed novel memories in the brain, a complex and precisely orchestrated molecular machinery is activated.
We have found that rapid down-regulation of Nogo receptor 1 (…
KAROLINSKA INSTITUTET
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