CORDIS Project
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This project seeks to improve melanoma diagnostics by developing a multiplexed imaging panel to analyze immune organization in tumors and lymph nodes. By leveraging machine learning, it aims to identify high-risk patients and enhance treatment decisions in clinical settings.
Malignant melanoma is a deadly disease with a 3% lifetime incidence.
Currently, no clinically approved companion diagnostics exist for immunotherapy in melanoma, and sentinel lymph node (sLN) evaluation remains the cornerstone of clinical decision-making. A sensitive, robust, and clinically applicable method for identifying patients at risk of developing metastatic disease is urgently needed.Studies in murine models have shown that lymph nodes (LNs) play a dual role in tumor immunity, both suppo…
WEIZMANN INSTITUTE OF SCIENCE
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