CORDIS Project
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This project investigates the origins and development of medulloblastoma, a common pediatric brain tumor, by creating animal models that mimic specific tumor subgroups. The research aims to identify the cell types involved in tumor formation and recurrence, ultimately improving treatment outcomes and reducing toxicitie…
MYC proteins like MYC and MYCN are transcription factors that are mis-regulated in more than half of all types of human cancer including medulloblastoma, the most common brain malignancy in children.
The two main challenges that can guide research in the field of pediatric brain tumors is improving survival and reducing long-term detriments due to treatment toxicities, especially from craniospinal radiotherapy.
Medulloblastoma is suggested to originate from specific cells in the small brain, cer…
UPPSALA UNIVERSITET
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