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The MediVAC project aims to identify and produce bioactive diterpenoids from the medicinal plant Vitex agnus-castus, which may help treat conditions like premenstrual syndrome and Parkinson's disease. It focuses on gene discovery and biotechnological production methods for these compounds.
Vitex agnus-castus (VAC) is a medicinal plant clinically shown to be an effective treatment for premenstrual syndrome.
The bioactive constituents are diterpenoids that can interact with G-protein-coupled receptors such as the dopamine D2 and D3 receptors.
This specific activity also opens up the possibility of other therapeutic applications where dopaminergic drugs are required, such as for the treatment of Parkinson’s disease and other movement disorders.
The major barrier to the development of…
KOBENHAVNS UNIVERSITET
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