CORDIS Project
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This project focuses on understanding how specific combinations of transcription factors regulate the expression of inflammatory genes in macrophages. By identifying and characterizing co-regulators involved in this process, the research aims to enhance our knowledge of gene transcription mechanisms in response to micr…
Tissue responses to microbial and endogenous danger signals involve the activation of both resident and monocyte-derived macrophages, as well as the coordinated inducible expression of hundreds of inflammatory genes.
Gene transcription is controlled by the information contained in thousands of genomic regulatory elements (enhancers and promoters), which is first read by transcription factors (TFs) and then integrated and relayed to the transcriptional machinery via an array of co-regulators wit…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Italy, Pieve Emanuele
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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