CORDIS Project
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This project investigates how mechanical stimuli affect bone healing, particularly in cases of delayed healing and age-related declines in sensitivity. By using advanced techniques to analyze the mechanical environment and molecular profiles in bone, it aims to develop new strategies for enhancing repair through target…
Delayed bone healing or failed non-unions account for 5 – 10% of all bone fractures and present a challenging problem in regenerative medicine.
Bone healing is a mechano-sensitive process; thus, mechanical stimuli can either enhance or impair fracture healing.
The molecular mechanisms underlying this phenomenon are complex and poorly understood.
Consequently, clinical applications which harness this mechano-sensitivity to enhance healing are limited.
It has also contributed to a lack of consensu…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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