CORDIS Project
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This project investigates how mechanical signals influence the fate of neural crest cells during embryonic development. By exploring the role of the actinomyosin skeleton and specific proteins, it aims to enhance understanding of cell differentiation and potential applications in tissue repair and addressing craniofaci…
Neural crest cells (NCC) are a unique vertebrate-specific population of multipotent cells that contribute to the development and evolution of the vertebrate head.
During embryonic development, cranial NCC give rise to a variety of hard and soft tissue cells including osteoblasts, chondrocytes, odontoblasts, glia and neuronal cells.
Whilst we understand a great deal about how growth factors and soluble chemicals determine the generation, migration, proliferation, survival and differentiation of t…
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