CORDIS Project
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This project investigates the mechanisms behind autoimmune diseases, focusing on the role of specific immune cells and potential treatments. It aims to enhance understanding of antigen tolerance and develop diagnostic tools and therapies for conditions like autoimmune pancreatitis and celiac disease.
An estimated 3-7% of Europe's population (80% females) suffer from autoimmune diseases (AID) that affect the body's various organs.
In healthy people, harmless proteins from self, bacterial flora or food do not elicit a destructive inflammatory response due to antigen tolerance.
Central to antigen tolerance is the function of regulatory T cells, a population of lymphocytes key to the prevention of excessive inflammatory tissue damage by immune effector cells.
Unfortunately, the mechanisms that s…
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