CORDIS Project
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This project investigates congenital heart defects in avian embryos to understand how altered blood flow affects heart development. It aims to develop in utero interventions that could restore blood flow and improve heart morphology before birth.
Congenital Heart Defects (CHD) are defects in the heart at birth affecting 1% of the population.
Majority of CHD do not have genetic origins suggesting that abnormal forces inside the developing heart due to altered blood flow is a major source.
Recent evidence via ultrasonography on suspected fetal hearts with cardiac defects has documented the worsening effects of cardiac malformations over gestation.
This has motivated the development of in utero interventions for CHD where the potential e…
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