CORDIS Project
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This research focuses on the interactions between the human immunodeficiency virus and host factors, particularly the APOBEC3G protein. It aims to uncover the mechanisms by which APOBEC3G inhibits viral replication, providing insights for new therapeutic strategies.
The human immunodeficiency virus (HIV) continues to be a major public health issue.
Current treatments can slow down disease progression, but high costs, severe side effects and the emergence of drug-resistant strains all call for the development of new treatment regimes.
The detailed understanding of virus-host interactions is of utmost importance for this endeavor.
The cytidine deaminase APOBEC3 (A3) proteins, and in particular APOBEC3G (A3G), are potent host restriction factors that can be pa…
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