CORDIS Project
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This project investigates the molecular mechanisms that define boundary cells in the hindbrain of zebrafish. It aims to understand how these boundaries function as organizing centers and their role in neuronal development through genetic mapping and time-lapse microscopy.
The Central Nervous System (CNS) is divided in different compartment structures:
Forebrain, Midbrain and Hindbrain.
The hindbrain in turn is subdivided in rhombomeres: compartmental structures separated by boundaries.
It has been described that another CNS compartment borders are organizing centres, but it’s unknown if the hindbrain boundaries have this role and which are the molecular mechanisms that specify this territory, to be distinguished from the remaining hindbrain cells.
Nevertheless, t…
MEDICAL RESEARCH COUNCIL
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