CORDIS Project
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This project investigates the plasticity of pediatric cancer cells, aiming to reverse their aggressive characteristics through advanced technologies like organoid models and single-cell genomics. By understanding and targeting the mechanisms of cell state changes, the research seeks to develop new therapeutic strategie…
IntroductionCancer cell plasticity, the ability of cancer cells to change their identity, enables tumors to adapt to hostile environments, aiding metastasis and resistance to treatments.
Hence, plasticity is a major unsolved problem frustrating effective treatment.
Unraveling the mechanisms underlying cancer cell plasticity is crucial to establish new avenues for cancer therapy.
In contrast to adult cancers, many pediatric tumors are driven by a single genetic alteration that fuels their aggress…
PrinsesMaximaCentrumvoorKinderoncologie
PRINSES MAXIMA CENTRUM VOOR KINDERONCOLOGIE BV
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