CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of transfer RNAs and their fragments in the activation of macrophages and the development of type 2 diabetes. By analyzing changes in these molecules in mouse models, the research aims to uncover how they influence inflammation and insulin resistance in obesity.
Obesity is a major public health concern and represents the strongest risk factor for type 2 diabetes (T2D) development.
In T2D pathogenesis, inflammation contributes to multi-organ insulin resistance and pancreatic β-cell failure.
Macrophages (Mφs) in adipose tissue and pancreatic islets play an important role in organ homeostasis, however their metabolic switch leads to chronic inflammation in obese individuals.
The functional profile of obese Mφs reflects a high complexity, not explained by t…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
