CORDIS Project
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This project focuses on the role of mast cells in various immune functions beyond allergies. It aims to utilize a newly developed mouse model that selectively lacks mast cells to investigate their contributions to immunity and disease.
Mast cells (MC) are best known for their central role in allergic disease but, more recently, MC have also been considered as important elements of the immune system in general.
Since the original recognition, more than 10 years ago, that MC may have immunological functions beyond allergic disease, a very long list of physiological and pathological conditions has been accumulated in which MC have been suggested to play important roles.
However, definitive evidence for MC functions in areas as im…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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