CORDIS Project
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This project aims to improve the diagnosis of Inflammatory Bowel Disease by identifying molecular biomarkers that differentiate between disease subtypes. By analyzing gene expression and promoter usage in colon biopsies, the project seeks to enable more accurate and targeted treatments for patients.
Inflammatory Bowel Disease (IBD) affects up to 1 in 200 individuals in Europe.
Current diagnosis of the two main subtypes of IBD (Crohn’s disease and ulcerative colitis) is based on endoscopy, radiology and the examination of biopsies with a high degree of uncertainty: 20% of patients are not classifiable or are rediagnosed later.
The uncertainty in diagnosis extends also to medication, which is to a large degree based on trial and error.
The use of molecular biomarkers could allow for an earlie…
KOBENHAVNS UNIVERSITET
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