CORDIS Project
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This project investigates the role of pulmonary veins in atrial fibrillation by studying the electrical activity of heart cells in different age groups. It aims to understand how these cells contribute to arrhythmias, particularly in the context of aging and hypertension.
In mammals, the complex anatomical structure connecting pulmonary veins (PVs) with the posterior wall of the left atrium (LA) of the heart, defined as LA-PV junction, is a source of electrical ectopic pulses, which initiate and maintain atrial fibrillation (AF), the most prominent sustained arrhythmia that worsens with tissue remodelling due to ageing and hypertension. PVs’ resident cardiomyocytes generate electrical pulses contributing to arrhythmogenesis within the LA-PV junction.
Moreover, “P…
KOBENHAVNS UNIVERSITET
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United Kingdom, Edinburgh
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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