CORDIS Project
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This project aims to understand the mechanisms of necrosis in neurodegenerative diseases, particularly as they relate to aging. By studying specific types of autophagy in model organisms, it seeks to uncover how these processes affect neuron vulnerability and longevity.
Necrosis contributes critically in devastating human pathologies such as stroke, ischemia, and age-associated neurodegenerative disorders.
Ageing increases susceptibility to neurodegeneration, in diverse species ranging from the lowly nematode Caenorhabditis elegans to humans.
The mechanisms that govern necrotic neurodegeneration and its modulation by ageing are poorly understood.
Autophagy has been implicated in necrosis and neurodegeneration, both with pro-survival and a pro-death roles.
Autop…
FOUNDATION FOR RESEARCH AND TECHNOLOGYHELLAS
IDRYMA TECHNOLOGIAS KAI EREVNAS
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