CORDIS Project
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This project investigates how proteins involved in cell signaling and adhesion in the nervous system interact and organize. By using advanced imaging techniques, it aims to reveal the molecular structures and mechanisms that govern these processes, potentially leading to new treatments for related neurological disorder…
Surface-attached proteins establish cell-to-cell contacts and generate signals to control development and function of tissues.
It is not clear how protein structure and interactions organize into intercellular assemblies to regulate signalling and adhesion.
Using a hybrid approach and focusing on two cell-signalling systems critical for nervous system function, I will determine how protein conformation, interaction and spatial arrangement form cis and trans assemblies to control intercellular ad…
UNIVERSITEIT UTRECHT
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