CORDIS Project
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This project focuses on manipulating gut microbiota to address imbalances associated with inflammatory bowel disease. By utilizing microbial communication signals, the aim is to restore healthy gut functions and reduce inflammation, offering a potential alternative to antibiotics.
Gut microbiota support intestinal tract development, immune system maturation, and protection against pathogens.
Imbalanced microbiota (dysbiosis) has a role in inflammatory bowel disease (IBD).
To control inflammation, patients take antibiotics, exacerbating dysbiosis, leading to loss of colonization resistance against pathogens and proliferation of pathobionts, disease development and progression.
Microbiota composition has, therefore, a very important role in host health, and strategies to ma…
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