CORDIS Project
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This project investigates axon regeneration mechanisms after spinal cord injury using magnetic nanoparticles to apply mechanical tension on growth cones. The goal is to understand how these physical cues influence axon growth, potentially leading to new therapies for spinal cord injuries.
The lack of axon regeneration following spinal cord injury (SCI) diminishes patients’ quality of life and poses a significant economic burden on the society.
This project aims to investigate the complex axon guidance mechanism following a SCI scenario by applying mechanical tension on the growth cones (GCs) of central nervous system (CNS) axons via novel magnetic nanoparticles that are functionalized with neuronal cell adhesion molecule.
It is hypothesized that the complex interaction of chemica…
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
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