CORDIS Project
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This project focuses on understanding the roles of macrophages, particularly microglia and border-associated macrophages, in the central nervous system. It aims to investigate their development, function, and impact on health and disease using advanced genetic and imaging techniques.
Macrophages are part of the mononuclear phagocyte system and play critical roles in innate immune responses.
They further exert crucial organ-specific functions to warrant tissue homeostasis.
Most macrophages are long-lived and derive from embryonic precursors.
The central nervous system (CNS) contains several macrophage populations, of which microglia are the most prominent and abundant population residing in the CNS parenchyma.
Besides being implicated in CNS pathologies, microglia guide neuro…
UNIVERSITAT ZURICH
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