CORDIS Project
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This project investigates the role of RNA modifications in regulating gene expression and cellular responses. By focusing on the dynamic modification m1A, the research aims to uncover its impact on translation regulation and how it interacts with other RNA modifications.
Reversible epigenetic modifications regulate gene expression to define cell fate and response to environmental stimuli.
Gene expression tuning by DNA and chromatin modifications is well studied, yet the effect of RNA modifications on gene expression is only starting to be revealed.
More than a hundred chemical modifications decorate RNAs, mainly non-coding ones, expanding their nucleotide vocabulary and mediating their diverse functions.
Several modifications were globally mapped in mRNA.
Only…
MEDICAL RESEARCH INFRASTRUCTURE DEVELOPMENT AND HEALTH SERVICES FUND BY THE SHEBA MEDICAL CENTER
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