CORDIS Project
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This project focuses on understanding the transcriptional control of immune cell development. By utilizing advanced genetic techniques, it aims to uncover the molecular networks that govern the differentiation of B and T cells, contributing to insights on immune responses and related diseases.
Acquired immunity to foreign pathogens depends on functional B and T cells.
The objective of this proposal is to elucidate the transcriptional control of lymphocyte development at three stages by deciphering the transcriptional networks specifying pro-B and pro-T cells in early lymphopoiesis and plasma cells in terminal B cell differentiation.To this end, we generated knock-in mice carrying a biotin acceptor sequence at the C-terminus of transcription factors, which can be biotinylated by transg…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
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