CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates how DNA is folded into chromosomes through a process called loop extrusion, driven by SMC complexes. By using advanced techniques, it aims to uncover the mechanisms behind this process and its implications for gene regulation and human health.
Since its discovery 150 years ago, DNA has been intensely studied.
As a result, it is understood in some detail how genomic DNA is replicated, repaired and segregated, and entire genomes can be sequenced.
However, how DNA is folded in chromosomes has remained a mystery.
It has been proposed that this is achieved by a process called loop extrusion.
This hypothesis proposes that SMC complexes, multi-subunit ATPases present in all kingdoms of life, reel genomic DNA into loops, thus bringing distant…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
