CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the 3D organization of DNA within cells, focusing on how specific proteins shape chromosomes. By employing single-molecule techniques, it aims to uncover the mechanics of DNA looping and ultimately build a chromosome from scratch, enhancing our understanding of genetic architecture.
How is DNA spatially organized in our cells?
What are the mechanisms that shape chromosomes and how does their 3D architecture direct their function?
Recent years have shown that the spatial structure of the genome is of pivotal importance for its biological function.
Yet, the basic physics of the formation and regulation of its 3D structure has remained unclear.
This proposal aims to understand the fundamental structure of chromosomes using a bottom up biophysics approach, from looping at the s…
TECHNISCHE UNIVERSITEIT DELFT
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
